The gut microbiota plays a pivotal role in human metabolic health by influencing immune responses, digestion, and metabolic homeostasis.Recent research highlights the intricate interactions between gut microbiota and RNA, especially non-coding RNAs, in regulating metabolic processes.Dysbiosis of the gut microbiota has been linked to metabolic disor
Metastatic colorectal adenocarcinoma tumor purity assessment from whole exome sequencing data.
Tumors rich in stroma are associated with advanced stage and poor prognosis in colorectal adenocarcinoma (CRC).Abundance of stromal cells also has implications for genomic analysis of patient tumors as it may prevent detection of somatic mutations.As part of our efforts to interrogate stroma-cancer cell interactions and to identify actionable thera
Protein Ingredients in Bread: Technological, Textural and Health Implications
The current lifestyle and trend for healthier foods has generated a growing consumer interest in acquiring bread products with a better nutritional composition, primarily products with high protein and fiber and low fat.Incorporating different protein sources as functional ingredients has improved the nutritional profile but may also affect the dou
Piscine Orthoreovirus from Western North America Is Transmissible to Atlantic Salmon and Sockeye Salmon but Fails to Cause Heart and Skeletal Muscle Inflammation.
Heart and skeletal muscle inflammation (HSMI) is a significant and often fatal disease of cultured Atlantic salmon in Norway.The consistent presence of Piscine orthoreovirus (PRV) in HSMI diseased fish along with the correlation of viral load and antigen with development of lesions has supported the supposition that PRV is the etiologic agent of th